*Tian Sang, Paul Beame, Henry Kautz*

The problem of Most Probable Explanation (MPE) arises in the scenario of probabilistic inference: finding an assignment to all variables that has the maximum likelihood given some evidence. We consider the more general CNF-based MPE problem, where each literal in a CNF-formula is associated with a weight. We describe reductions between MPE and weighted MAX-SAT, and show that both can be solved by a variant of weighted model counting. The MPE-SAT algorithm is quite competitive with the state-of-the-art MAX-SAT, WCSP, and MPE solvers on a variety of problems.